|The One Electronic, among others|
I believe - along with folks like Scot McCloud and Neil Gaiman - that webcomics are where it's truly at in terms of TNBT - The Next Big Thing. Not just as an incubator for talent that will then migrate on to Marvel or DC or Vertigo, but as a form in itself. Artists like Kate Beaton, Egypt Urnash...and a personal favorite, Evan Dahm.
Check out Evan especially. He is just...unique.